Phosphino‐Phosphination Reactions: Frustrated Lewis Pair Reactivity of Phosphino‐Phosphonium Cations with Alkynes
Hyehwang Kim, Zheng‐Wang Qu, Stefan Grimme, Nahil Al‐Zuhaika, Douglas W. Stephan
Abstract
Abstract The phosphino‐phosphonium cations of the form [R 3 PPR′ 2 ] + are labile and provide access to the constituent Lewis acidic and Lewis basic fragments. This permits frustrated Lewis pair‐type addition reactions to alkynes, affording unprecedented phosphino‐phosphination reactions and giving cations of the form [ cis‐ R 3 PCHC(R′′)PR′ 2 ] + . This reactivity is further adapted to prepare several examples of a rare class of dissymmetric cis‐ olefin‐linked bidentate phosphines.
Topics & Concepts
PhosphoniumReactivity (psychology)ChemistryLewis acids and basesFrustrated Lewis pairDenticityOlefin fiberCyclobutanoneMedicinal chemistryPolymer chemistryOrganic chemistryCatalysisCrystal structureRing (chemistry)Alternative medicineMedicinePathologyOrganoboron and organosilicon chemistrySynthesis and characterization of novel inorganic/organometallic compoundsAsymmetric Synthesis and Catalysis