Hypoxia as a potential inducer of immune tolerance, tumor plasticity and a driver of tumor mutational burden: Impact on cancer immunotherapy
Raefa Abou Khouzam, Bassam Janji, Jérôme Thiery, Rania Faouzi Zaarour, Ali N. Chamseddine, Hemma Mayr, Pierre Savagner, Claudine Kiéda, Sophie Gad, Stéphanie Buart, Jean‐Maríe Lehn, Përparim Limani, Salem Chouaı̈b
Topics & Concepts
Tumor microenvironmentImmune systemImmunotherapyBiologyCancer researchTumor hypoxiaCancer immunotherapyHypoxia (environmental)CancerAngiogenesisCancer cellImmunogenicityStromal cellImmunologyImmune toleranceMedicineInternal medicineRadiation therapyChemistryGeneticsOrganic chemistryOxygenCancer, Hypoxia, and MetabolismImmune cells in cancerCancer Immunotherapy and Biomarkers