Blood group ABO polymorphism inhibits SARS‐CoV‐2 infection and affects COVID‐19 progression
Fumiichiro Yamamoto, Miyako Yamamoto, Eduardo Muñiz‐Díaz
Abstract
The ABO blood group system consists of glycan antigens A and B and polyclonal antibodies against these antigens in individuals who do not express the antigens (Landsteiner's law). A and B antigens can also be expressed on other types of cells than RBCs, including epithelial cells of the gastrointestinal and respiratory tracts and endothelial cells lining the blood vessels. Therefore, ABO matching is also crucial for cell/tissue/organ transplantation, in addition to RBC transfusion.
Topics & Concepts
Library scienceMedicineCoronavirus disease 2019 (COVID-19)Computer scienceInternal medicineDiseaseInfectious disease (medical specialty)Blood groups and transfusionCOVID-19 Clinical Research StudiesNeonatal Health and Biochemistry