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Design, synthesis, and biological evaluation of N-(4-substituted)-3-phenylisoxazolo[5,4–d]pyrimidin-4-amine derivatives as apoptosis-inducing cytotoxic agents

Nikhil Baliram Gaikwad, Sapana Bansod, Alekhya Mara, Ramana Garise, Nanduri Srinivas, Chandraiah Godugu, Venkata Madhavi Yaddanapudi

2021Bioorganic & Medicinal Chemistry Letters14 citationsDOI

Topics & Concepts

ChemistryApoptosisAcridine orangeDAPICell cultureCancer cellMechanism of actionStereochemistryEthidium bromideGrowth inhibitionCancer researchBiochemistryCancerIn vitroDNAGeneticsBiologyMedicineInternal medicineProtein Degradation and InhibitorsClick Chemistry and ApplicationsQuinazolinone synthesis and applications
Design, synthesis, and biological evaluation of N-(4-substituted)-3-phenylisoxazolo[5,4–d]pyrimidin-4-amine derivatives as apoptosis-inducing cytotoxic agents | Litcius