m<sup>6</sup>A-RNA Demethylase FTO Inhibitors Impair Self-Renewal in Glioblastoma Stem Cells
Sarah Huff, Shashi Kant Tiwari, Gwendolyn González, Yinsheng Wang, Tariq M. Rana
Abstract
levels in GSCs consistent with FTO inhibition. These results support FTO-04 as a potential new lead for treatment of glioblastoma.
Topics & Concepts
DemethylaseGlioblastomaStem cellRNACancer researchCell biologyChemistryBiologyBiochemistryGeneEpigeneticsRNA modifications and cancerHVDC Systems and Fault ProtectionRNA Research and Splicing