FGFR1/MAPK-directed brachyury activation drives PD-L1-mediated immune evasion to promote lung cancer progression
Yunping Hu, Yong Lu, Fei Xing, Wesley Hsu
Topics & Concepts
BrachyuryMAPK/ERK pathwayCancer researchImmune systemLung cancerPD-L1T cellCD8BiologyImmunotherapyImmunologyKinaseMedicineCell biologyInternal medicineBiochemistryEmbryonic stem cellGeneMesodermCancer Immunotherapy and BiomarkersImmune cells in cancerFibroblast Growth Factor Research