eccDNAs are apoptotic products with high innate immunostimulatory activity
Yuangao Wang, Meng Wang, Mohamed Nadhir Djekidel, Huan Chen, Di Liu, Frederick W. Alt, Yi Zhang
Topics & Concepts
Innate immune systemBiogenesisDNA ligaseBiologyDNAExtrachromosomal DNADNA fragmentationGenomeCell biologyDNA sequencingComputational biologyGeneticsApoptosisGeneImmune systemProgrammed cell deathAdvanced biosensing and bioanalysis techniquesRNA Interference and Gene DeliveryImmunotherapy and Immune Responses