Natural Product Synthesis: The Endless Quest for Unreachable Perfection
Nicolas Fay, Cyrille Kouklovsky, Aurélien de la Torre
Abstract
Total synthesis is a field in constant progress. Its practitioners aim to develop ideal synthetic strategies to build complex molecules. As such, they are both a driving force and a showcase of the progress of organic synthesis. In this Perspective, we discuss recent notable total syntheses. The syntheses selected herein are classified according to the key strategic considerations for each approach.
Topics & Concepts
PerfectionIdeal (ethics)Total synthesisProduct (mathematics)Perspective (graphical)Field (mathematics)Computer scienceNatural (archaeology)Key (lock)Management scienceBiochemical engineeringNanotechnologyEngineeringEpistemologyChemistryArtificial intelligenceMathematicsPhilosophyComputer securityMaterials scienceOrganic chemistryGeographyGeometryArchaeologyPure mathematicsAdvanced Synthetic Organic ChemistryChemical synthesis and alkaloidsMicrobial Natural Products and Biosynthesis