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Single-molecule states link transcription factor binding to gene expression

Benjamin R. Doughty, Michaela M. Hinks, Julia M. Schaepe, Georgi K. Marinov, Abby R. Thurm, Carolina Rios-Martinez, Benjamin Parks, Yingxuan Tan, Emil Marklund, Danilo Dubocanin, Lacramioara Bintu, William J. Greenleaf

2024Nature32 citationsDOIOpen Access PDF

Topics & Concepts

EnhancerTranscription factorCooperativityCooperative bindingBinding siteDNA binding siteChromatinNucleosomeBiologyRegulation of gene expressionGene expressionFootprintingResponse elementPromoterChemistryGeneticsGeneMolecular biologyGenomics and Chromatin DynamicsAdvanced biosensing and bioanalysis techniquesProtein Degradation and Inhibitors
Single-molecule states link transcription factor binding to gene expression | Litcius