<i>In situ</i> self-assembly of polydopamine inside injectable hydrogels: antibacterial activity and photothermal therapy for superbug-infected wound healing
Yi Zhu, Ling Lin, Yuntao Xie, Qinghua Wang, Chenghong Gu, Yu Chen, Yeping Song, Guohao Han, Weipeng Lu, Yanchuan Guo
Abstract
self-assembly, the size of the PDA NPs increases (>200 nm), eventually giving the gel an efficient photothermal therapy effect. Moreover, the gel presents a relatively strong wet adhesion (63 kPa), superior biocompatibility and non-immunogenicity. This work offers innovative insights into the antibacterial mechanism of SC-PDA NPs and provides a novel design for constructing safe antibacterial hydrogel wound dressings, demonstrating great potential applications in superbug-infected wound healing.
Topics & Concepts
Photothermal therapySelf-healing hydrogelsWound healingIn situSelf-healingAntibacterial activityChemistryNanotechnologyMicrobiologyBacteriaMaterials scienceMedicinePolymer chemistryBiologySurgeryPathologyOrganic chemistryAlternative medicineGeneticsHydrogels: synthesis, properties, applicationsPolymer Surface Interaction StudiesWound Healing and Treatments