A phosphine-free iron complex-catalyzed synthesis of cycloalkanes<i>via</i>the borrowing hydrogen strategy
Léo Bettoni, Sylvain Gaillard, Jean‐Luc Renaud
Abstract
Herein we report a diaminocyclopentadienone iron tricarbonyl complex catalyzed synthesis of substituted cyclopentane, cyclohexane and cycloheptane compounds using the borrowing hydrogen strategy in the presence of various substituted primary and secondary 1,n diols as alkylating reagents. Deuterium labeling experiments confirm that the diols were the hydride source in this cascade process.
Topics & Concepts
CyclopentaneCycloheptaneCyclohexaneCatalysisPhosphineCyclooctaneChemistryMethylcyclopentaneHydrogenPrimary (astronomy)ReagentCycloalkaneOrganic chemistryCombinatorial chemistryMedicinal chemistryIsomerizationAstronomyPhysicsAsymmetric Hydrogenation and CatalysisCarbon dioxide utilization in catalysisOrganoboron and organosilicon chemistry