Advancements in Systemic Therapy for Pancreatic Cancer
Timothy J. Brown, Kim A. Reiss, Mark H. O’Hara
Abstract
Outcomes for patients with advanced pancreatic cancer have improved in the past 12 years, mainly because of progress made in systemic therapies. New treatment strategies for advanced pancreatic cancer include switch maintenance with cytotoxic therapies, induction maintenance, and the utilization of targeted agents for patients with actionable variants, as well as ongoing development of cytotoxic regimens, such as NALIRIFOX. The activity of immunotherapy has been disappointing to date, but novel combinations and identifying appropriate patient populations may further unlock its potential.
Topics & Concepts
Pancreatic cancerMedicineImmunotherapyCancerCytotoxic T cellTargeted therapyOncologySystemic therapyIntensive care medicineInternal medicineBiologyIn vitroBiochemistryBreast cancerPancreatic and Hepatic Oncology ResearchCancer Immunotherapy and BiomarkersNeuroblastoma Research and Treatments