The Cell–Cell Communication Signal Indole Controls the Physiology and Interspecies Communication of Acinetobacter baumannii
Binbin Cui, Xiayu Chen, Quan Guo, Shihao Song, Mingfang Wang, Jingyun Liu, Yinyue Deng
Abstract
expression at the transcriptional levels. Furthermore, indole represses the QS systems and type III secretion system (T3SS) of P. aeruginosa and enhances the competitive ability of A. baumannii. Together, our work describes a QS signaling network where a pathogen uses to control the bacterial physiology and pathogenesis, and the competitive ability in microbial community.
Topics & Concepts
Acinetobacter baumanniiQuorum sensingIndole testMicrobiologyBiologyVirulenceTryptophanasePseudomonas aeruginosaHomoserineEscherichia coliMutantChromobacterium violaceumTryptophanTryptophan synthaseBacteriaBiochemistryGeneGeneticsAmino acidBacterial biofilms and quorum sensingAntibiotic Resistance in BacteriaVibrio bacteria research studies