Litcius/Paper detail

Photocatalyst- and Transition-Metal-Free Visible-Light-Promoted Intramolecular C(sp<sup>2</sup>)–S Formation

Hao Wang, Qi Wu, Jiandong Zhang, Haiyan Li, Hong‐Xi Li, Hong-Xi Li, Hong-Xi Li

2021Organic Letters41 citationsDOI

Abstract

A photocatalyst- and transition-metal-free visible-light-induced cyclization of ortho-halothiobenzanilides has been developed. Upon irradiation with visible light, substrates undergo dehalogenative cyclization to 2-aryl benzothiazoles with high efficiency and selectivity. This photocyclization exhibits a high tolerance to various functional groups, is applicable for the synthesis of 2-alkyl benzothiazoles, and is easy to set up for gram-scale reaction.

Topics & Concepts

ChemistryPhotocatalysisVisible spectrumIntramolecular forcePhotochemistryAlkylTransition metalArylIrradiationSelectivityCombinatorial chemistryCatalysisStereochemistryOrganic chemistryOptoelectronicsPhysicsNuclear physicsRadical Photochemical ReactionsSulfur-Based Synthesis TechniquesCatalytic C–H Functionalization Methods