Toward Amines, Imines, and Imidazoles: A Viewpoint on the 3d Transition-Metal-Catalyzed Homogeneous Hydrogenation of Nitriles
Jorge A. Garduño, Juventino J. Garcı́a
Abstract
Mn-, Fe-, Co-, and Ni-based catalytic precursors have been reported for the homogeneous 3d transition-metal-catalyzed hydrogenation of nitriles. We present herein a critical assessment of such reports, emphasizing experimental setups, selectivity patterns, and mechanistic aspects fashioning this growing field. Moreover, its successes, drawbacks, and challenges are highlighted to outline what is next in the design of catalytic systems for future years.
Topics & Concepts
CatalysisHomogeneousTransition metalSelectivityHomogeneous catalysisCombinatorial chemistryChemistryOrganic chemistryMaterials scienceComputational chemistryPhysicsThermodynamicsAsymmetric Hydrogenation and CatalysisNanomaterials for catalytic reactionsCatalysis for Biomass Conversion