Discovery and Anticancer Activity of Novel 1,3,4-Thiadiazole- and Aziridine-Based Indolin-2-ones <i>via In Silico</i> Design Followed by Supramolecular Green Synthesis
Prashant Chaudhari, Sanjay B. Bari, Sanjay J. Surana, Atul A. Shirkhedkar, Chandrakant Bonde, Saurabh C. Khadse, Vinod G. Ugale, Akhil Nagar, Rameshwar S. Cheke
Abstract
, and the results suggested that these two compounds could be potential leads for the treatment of cancer.
Topics & Concepts
ChemistryAziridineStereochemistryQuinoxalineDocking (animal)Supramolecular chemistryCombinatorial chemistryMoleculeRing (chemistry)Organic chemistryMedicineNursingClick Chemistry and ApplicationsSynthesis and Catalytic ReactionsQuinazolinone synthesis and applications