Hypobaric hypoxia drives selection of altitude-associated adaptative alleles in the Himalayan population
Samantha Sharma, Remya Koshy, Rahul Kumar, Ghulam Mohammad, Tashi Thinlas, Brian B. Graham, Qadar Pasha
Topics & Concepts
BiologySingle-nucleotide polymorphismAlleleAltitude (triangle)PopulationEffects of high altitude on humansGeneticsGeneBalancing selectionAdaptation (eye)Genetic variationIn silicoHypoxia (environmental)Evolutionary biologyGenotypeMedicineOxygenChemistryEnvironmental healthNeuroscienceMathematicsGeometryOrganic chemistryAnatomyHigh Altitude and HypoxiaNeuroscience of respiration and sleepHeme Oxygenase-1 and Carbon Monoxide