A Comprehensive Assessment of Right Ventricular Function in Chronic Thromboembolic Pulmonary Hypertension
Stella Marchetta, Tom Verbelen, Guido Claessen, Rozenn Quarck, Marion Delcroix, Laurent Godinas
Abstract
While chronic thromboembolic pulmonary hypertension (CTEPH) results from macroscopic and microscopic obstruction of the pulmonary vascular bed, the function of the right ventricle (RV) and increased RV afterload are the main determinants of its symptoms and prognosis. In this review, we assess RV function in patients diagnosed with CTEPH with a focus on the contributions of RV afterload and dysfunction to the pathogenesis of this disease. We will also discuss changes in RV function and geometry in response to treatment, including medical therapy, pulmonary endarterectomy, and balloon pulmonary angioplasty.
Topics & Concepts
MedicineChronic thromboembolic pulmonary hypertensionCardiologyPulmonary hypertensionVentricleInternal medicineAfterloadAngioplastyPulmonary arteryEndarterectomyPulmonary function testingPathogenesisStenosisPulmonary Hypertension Research and TreatmentsCardiovascular Function and Risk FactorsCardiac Valve Diseases and Treatments