Magnetic wire active microrheology of human respiratory mucus
Milad Radiom, Romain Hénault, Salma Mani, Aline Grein-Iankovski, Xavier Norel, Jean‐François Berret
Abstract
) measurements, leading to the evaluation of the mucin network relaxation time. This relaxation time is found to be widely distributed, from one to several hundred seconds. Mucus is identified as a viscoelastic liquid with an elastic modulus of 2.5 ± 0.5 Pa and a static viscosity of 100 ± 40 Pa s. Our work shows that beyond the established spatial variations in rheological properties due to microcavities, mucus exhibits secondary inhomogeneities associated with the relaxation time of the mucin network that may be important for its flow properties.
Topics & Concepts
MicrorheologyViscoelasticityMucusMucinRheologyMaterials scienceViscosityRelaxation (psychology)BiophysicsChemistryNanotechnologyComposite materialBiologyNeuroscienceEcologyBiochemistryInhalation and Respiratory Drug DeliveryCystic Fibrosis Research AdvancesDysphagia Assessment and Management