The self-adjuvant heterocyclic lipid nanoparticles encapsulated with vaccine and STAT3 siRNA boost cancer immunotherapy through DLN-targeted and STING pathway
Zixu Liu, Qingqing Wang, Yupeng Feng, Linxuan Zhao, Nan Dong, Yu Zhang, Tian Yin, Haibing He, Xing Tang, Jingxin Gou, Yang Li
Topics & Concepts
Cancer immunotherapyImmunotherapyCancer researchTumor microenvironmentCross-presentationAntigen presentationAntigenAdjuvantImmune systemSTAT3Cancer vaccineImmunologyMedicineSignal transductionT cellBiologyCell biologyinterferon and immune responsesImmunotherapy and Immune ResponsesCytokine Signaling Pathways and Interactions