Cross-dehydrogenative coupling enables enantioselective access to CF<sub>3</sub>-substituted all-carbon quaternary stereocenters
Xiaoguang Pan, Zehua Wang, Linglong Kan, Ying Mao, Yasheng Zhu, Lei Liu
Abstract
A cross-dehydrogenative coupling (CDC) strategy for enantioselective access to acyclic CF<sub>3</sub>-substituted all-carbon quaternary stereocenters has been established.
Topics & Concepts
StereocenterEnantioselective synthesisQuaternary carbonQuaternaryCoupling (piping)Carbon fibersCombinatorial chemistryStereochemistryChemistryComputer scienceMaterials scienceOrganic chemistryCatalysisAlgorithmBiologyPaleontologyMetallurgyComposite numberCatalytic C–H Functionalization MethodsFluorine in Organic ChemistryAsymmetric Hydrogenation and Catalysis