Curcumin-PLGA based nanocapsule for the fluorescence spectroscopic detection of dopamine
Hanine Zakaria, Riham El Kurdi, Digambara Patra
Abstract
It was noticed that increasing the concentration of the different molecules had no significant change in the fluorescence signal of the nanocapsules. These results confirm the strong quenching between dopamine and curcumin in the nanocapsules. Hence, this fluorescence emission technique was found to be selective, easy and fast with low cost for the determination of dopamine in a concentration range up to 5 mM with a detection limit equal to 22 nM.
Topics & Concepts
CurcuminDopamineFluorescencePLGAChemistryNanotechnologyPharmacologyMaterials scienceMedicineBiochemistryInternal medicinePhysicsIn vitroQuantum mechanicsCurcumin's Biomedical ApplicationsAdvanced Drug Delivery SystemsSupramolecular Self-Assembly in Materials