Litcius/Paper detail

Genomics enters the deep learning era

Etienne Routhier, Julien Mozziconacci

2022PeerJ40 citationsDOIOpen Access PDF

Abstract

The tremendous amount of biological sequence data available, combined with the recent methodological breakthrough in deep learning in domains such as computer vision or natural language processing, is leading today to the transformation of bioinformatics through the emergence of deep genomics, the application of deep learning to genomic sequences. We review here the new applications that the use of deep learning enables in the field, focusing on three aspects: the functional annotation of genomes, the sequence determinants of the genome functions and the possibility to write synthetic genomic sequences.

Topics & Concepts

Deep learningAnnotationGenomicsComputer scienceArtificial intelligenceGenomeSequence (biology)Computational biologyFunctional genomicsData scienceComputational genomicsTransformation (genetics)BiologyGeneticsGeneGenomics and Phylogenetic StudiesRNA and protein synthesis mechanismsMachine Learning in Bioinformatics