Designed variants of ACE2-Fc that decouple anti-SARS-CoV-2 activities from unwanted cardiovascular effects
Pan Liu, Xinfang Xie, Li Gao, Jin Jing
Topics & Concepts
VirusAngiotensin-converting enzyme 2EnzymeRecombinant DNAViral entryReceptorAntibodySevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)CoronavirusVirologyBiologyChemistryCoronavirus disease 2019 (COVID-19)PharmacologyImmunologyBiochemistryViral replicationMedicineInternal medicineGeneDiseaseInfectious disease (medical specialty)SARS-CoV-2 and COVID-19 ResearchCOVID-19 Clinical Research StudiesCAR-T cell therapy research