Visible-Light-Promoted Thiolation of Benzyl Chlorides with Thiosulfonates via a Photoactive Electron Donor–Acceptor Complex
Chao Gong, Jialun Huang, Liuyan Cai, Yilong Yuan, Tonglv Pu, Mingjie Huang, Si‐Hai Wu, Lianhui Wang
Abstract
Visible-light-promoted thiolation of benzyl chlorides with thiosulfonates is disclosed via an electron donor-acceptor complex strategy. In addition to efficiently delivering a series of arylbenzylsulfide compounds, versatile thioglycosides were also successfully constructed by applying the metal- and photocatalyst-free protocol. Preliminary mechanistic studies suggest that a radical-radical coupling process was involved in this transformation.
Topics & Concepts
ChemistryPhotochemistryPhotocatalysisElectron donorVisible spectrumAcceptorCombinatorial chemistryElectron acceptorCatalysisOrganic chemistryCondensed matter physicsPhysicsOptoelectronicsSulfur-Based Synthesis TechniquesRadical Photochemical ReactionsChemical Synthesis and Reactions