Magic shotgun approach to anti-inflammatory pharmacotherapy: Synthesis of novel thienopyrimidine monomers/heterodimer as dual COX-2 and 15-LOX inhibitors endowed with potent antioxidant activity
Sara Elsayed, Ahmed S. Abdelkhalek, Samar Rezq, Mansour E. Abu Kull, Damián G. Romero, Hend Kothayer
Topics & Concepts
ChemistryStereochemistryPharmacologyMedicineSynthesis and biological activityInflammatory mediators and NSAID effectsSynthesis and Biological Evaluation