Inhibition of protein phosphatase-2A with LB-100 enhances antitumor immunity against glioblastoma
Dominic Maggio, Winson S. Ho, Rebecca Breese, Stuart Walbridge, Herui Wang, Jing Cui, John D. Heiss, Mark R. Gilbert, John S. Kovach, Rongze Lu, Zhuang Zhengping
Topics & Concepts
BlockadeGliomaCancer researchImmunotherapyMedicineCD8Protein phosphatase 2Immune checkpointCombination therapyImmune systemImmunologyPhosphatasePharmacologyBiologyReceptorInternal medicinePhosphorylationBiochemistryProtein Tyrosine PhosphatasesCancer Immunotherapy and BiomarkersCytokine Signaling Pathways and Interactions