Rational design of cannabinoid type-1 receptor allosteric modulators: Org27569 and PSNCBAM-1 hybrids
Thuy Nguyen, Thomas F. Gamage, Ann M. Decker, David B. Finlay, Tiffany L. Langston, Daniel G. Barrus, Michelle Glass, Danni L. Harris, Yanan Zhang
Topics & Concepts
Allosteric regulationChemistryIn silicoDocking (animal)Cannabinoid receptorPharmacophoreBinding siteCannabinoidComputational biologyStereochemistryReceptorBiochemistryAgonistBiologyGeneNursingMedicineCannabis and Cannabinoid ResearchPharmacological Receptor Mechanisms and EffectsNeuroscience and Neuropharmacology Research