HERC1 Ubiquitin Ligase Is Required for Hippocampal Learning and Memory
Eva M. Pérez-Villegas, Mikel Pérez-Rodríguez, José Vicente Negrete‐Díaz, Rocío Ruiz, José Luís Rosa, Guillermo Álvarez de Toledo, Antonio Rodríguez-Moreno, José Á. Armengol
Abstract
hippocampus differ relative to the control mice. Together, these observations demonstrate the important role of HERC1 in regulating synaptic activity during learning.
Topics & Concepts
NeuroscienceHippocampal formationHippocampusDendritic spineDentate gyrusMorris water navigation taskBiologyLong-term potentiationNeocortexGlutamatergicGlutamate receptorReceptorBiochemistryGenetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology ResearchAutophagy in Disease and Therapy