The Effect of γ-Aminobutyric Acid Intake on UVB- Induced Skin Damage in Hairless Mice
Hairu Zhao, Bomi Park, Min-Jung Kim, Seok-Hyun Hwang, Tae‐Jong Kim, Seung-Un Kim, Iksun Kwon, Jae Sung Hwang
Abstract
experiments showed that oral administration of GABA significantly improved skin wrinkles and epidermal thickness. After the intake of GABA, there was a significant decrease observed in the increase of skin thickness measured by calipers and erythema. Additionally, the decrease in skin moisture and elasticity in hairless mice exposed to UVB radiation was also significantly restored. Overall, this study demonstrates the potential of GABA as functional food material for improving skin aging and moisturizing.
Topics & Concepts
HairlessDermisPhotoagingTransepidermal water lossSkin AgingErythemaIn vivoHyperpigmentationHuman skinWrinkleChemistryPharmacologyMatrix metalloproteinaseFilaggrinDermatologyMedicineBiochemistryBiologyPathologyStratum corneumAtopic dermatitisGerontologyGeneticsBiotechnologySkin Protection and AgingBee Products Chemical AnalysisDermatology and Skin Diseases