Mechanisms, functions and therapeutic targeting of protein tyrosine phosphatases
Tony Tiganis, Nicholas K. Tonks
Topics & Concepts
Protein tyrosine phosphataseReceptor tyrosine kinaseTyrosineBiologyTyrosine kinaseCell biologyJAK-STAT signaling pathwayKinaseSignallingGRB10BiochemistryPhosphataseCellSH2 domainProto-oncogene tyrosine-protein kinase SrcSignal transductionChemistryPlatelet-derived growth factor receptorSH3 domainPhosphorylationProtein kinase AReceptor Protein-Tyrosine KinasesComputational biologyProtein Tyrosine PhosphatasesGalectins and Cancer BiologyMacrophage Migration Inhibitory Factor