Additive manufacturing of barium-doped calcium silicate/poly-ε-caprolactone scaffolds to activate CaSR and AKT signalling and osteogenic differentiation of mesenchymal stem cells
Yung‐Cheng Chiu, Yen-Hong Lin, Yi‐Wen Chen, Ting-You Kuo, Ming‐You Shie
Abstract
performance of the proposed scaffolds was assessed using micro-CT and histological slices, which revealed that the BaCS scaffolds could further enhance bone regeneration, compared with bare scaffolds. These results suggest the potential use of 3D-printed BaCS/PCL scaffolds as next-generation substitutes for bone regeneration.
Topics & Concepts
Mesenchymal stem cellBariumMaterials scienceCalciumCell biologyDopingBiomedical engineeringMetallurgyOptoelectronicsBiologyMedicineBone Tissue Engineering MaterialsElectrospun Nanofibers in Biomedical Applications3D Printing in Biomedical Research