Deciphering Acetaminophen-Induced Hepatotoxicity: The Crucial Role of Transcription Factors like Nuclear Factor Erythroid 2–Related Factor 2 as Genetic Determinants of Susceptibility to Drug-Induced Liver Injury
Ankit P. Laddha, Hangyu Wu, José E. Manautou
Topics & Concepts
AcetaminophenPharmacologyOxidative stressLiver injuryToxicityTranscription factorKEAP1GlutathioneMedicineBiologyBiochemistryEnzymeGeneInternal medicineGenomics, phytochemicals, and oxidative stressDrug-Induced Hepatotoxicity and ProtectionPharmacogenetics and Drug Metabolism