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When E-Cadherin Becomes Unstuck in Cancer

Lorraine O’Driscoll

2020New England Journal of Medicine15 citationsDOI

Abstract

Changes in cell adhesion have long been a focus of molecular biologists who seek to understand the mechanisms of metastasis. Two recent studies of the cell-adhesion molecule E-cadherin have yielded some interesting results.

Topics & Concepts

CadherinMedicineCell adhesion moleculeCell adhesionCancerMetastasisFocus (optics)AdhesionCancer researchCellImmunologyBiologyGeneticsInternal medicineChemistryOpticsPhysicsOrganic chemistryWnt/β-catenin signaling in development and cancerCell Adhesion Molecules ResearchCaveolin-1 and cellular processes
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