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Structural basis of biased T cell receptor recognition of an immunodominant HLA-A2 epitope of the SARS-CoV-2 spike protein

Priyanka Chaurasia, Thi H. O. Nguyen, Louise C. Rowntree, Jennifer A. Juno, Adam K. Wheatley, Stephen J. Kent, Katherine Kedzierska, Jamie Rossjohn, Jan Petersen

2021Journal of Biological Chemistry44 citationsDOIOpen Access PDF

Abstract

peptide.

Topics & Concepts

EpitopeT-cell receptorBiologyHuman leukocyte antigenCD8T cellImmunodominanceVirologyAntigenImmune systemImmunologySARS-CoV-2 and COVID-19 ResearchCOVID-19 Clinical Research Studiesvaccines and immunoinformatics approaches
Structural basis of biased T cell receptor recognition of an immunodominant HLA-A2 epitope of the SARS-CoV-2 spike protein | Litcius