A versatile nanoplatform with excellent biofilm permeability and spatiotemporal ROS regulation for peri-implantitis treatment
Zeyu Han, Ying Li, Xin Zhan, Ming Sun, Yan Liang, Mujie Yuan, Yong Sun, Jie Cao, Baodong Zhao, Li Fan
Abstract
Given the pathogenesis of PI, this strategy rationally designed a multifunctional NP with antibacterial and anti-inflammatory functions via spatiotemporal ROS regulation. It provides a potentially novel approach for PI treatment, which may have a profound impact on improving the prognosis of patients with PI and advancing the field of implant dentistry.
Topics & Concepts
Peri-implantitisBiofilmPeriChemistryNanotechnologyCell biologyMedicineMaterials scienceBiologyImplantInternal medicineSurgeryBacteriaGeneticsBone Tissue Engineering MaterialsDental Implant Techniques and OutcomesAdvanced biosensing and bioanalysis techniques