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Brain Chimeroids reveal individual susceptibility to neurotoxic triggers

Noelia Antón-Bolaños, Irene Faravelli, Tyler Faits, Sophia Andreadis, Rahel Kästli, Sebastiano Trattaro, Xian Adiconis, Anqi Wei, Abhishek Sampath Kumar, Daniela J. Di Bella, Matthew Tegtmeyer, Ralda Nehme, Joshua Z. Levin, Aviv Regev, Paola Arlotta

2024Nature86 citationsDOIOpen Access PDF

Topics & Concepts

OrganoidInduced pluripotent stem cellBiologyHuman brainPhenotypeCell typeProgenitor cellNeuroscienceStem cellNeural stem cellCellEmbryonic stem cellGeneticsGenePluripotent Stem Cells ResearchSingle-cell and spatial transcriptomicsGenetics, Aging, and Longevity in Model Organisms
Brain Chimeroids reveal individual susceptibility to neurotoxic triggers | Litcius