Vitamin C May Increase the Recovery Rate of Outpatient Cases of SARS-CoV-2 Infection by 70%: Reanalysis of the COVID A to Z Randomized Clinical Trial
Harri Hemilä, Anitra C. Carr, Elizabeth Chalker
Abstract
Given the previous research on vitamin C, we read with great interest the report on the COVID A to Z Randomized Clinical Trial (COVID A to Z trial) which investigated the effects of 8 g/day vitamin C on the recovery from outpatient SARS-CoV-2 infection (9). However, we unfortunately found several methodological shortcomings in the trial. Here we describe our major concerns and statistical reanalysis of the findings.
Topics & Concepts
Coronavirus disease 2019 (COVID-19)MedicineRandomized controlled trialSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)2019-20 coronavirus outbreakClinical trialInfection rateRecovery rateInternal medicineSurgeryVirologyOutbreakChemistryInfectious disease (medical specialty)DiseaseChromatographyVitamin C and Antioxidants ResearchClimate Change and Health ImpactsLong-Term Effects of COVID-19