Copper enhances aggregational toxicity of mutant huntingtin in a Drosophila model of Huntington's Disease
Amanda G. Lobato, Natalie Ortiz-Vega, Yi Zhu, Deepa Neupane, Katlyn K. Meier, R. Grace Zhai
Topics & Concepts
HuntingtinNeurodegenerationMutantHuntington's diseaseAutophagyHuntingtin ProteinCopper toxicityChemistryCopperProtein aggregationTrinucleotide repeat expansionCell biologyToxicityAmyloid (mycology)BiologyBiochemistryGeneDiseaseMedicinePathologyOrganic chemistryInorganic chemistryApoptosisAlleleGenetic Neurodegenerative DiseasesMitochondrial Function and PathologyAmyotrophic Lateral Sclerosis Research