Super-resolution imaging of bacterial pathogens and visualization of their secreted effectors
Moirangthem Kiran Singh, Linda J. Kenney
Abstract
Recent advances in super-resolution imaging techniques, together with new fluorescent probes have enhanced our understanding of bacterial pathogenesis and their interplay within the host. In this review, we provide an overview of what these techniques have taught us about the bacterial lifestyle, the nucleoid organization, its complex protein secretion systems, as well as the secreted virulence factors.
Topics & Concepts
EffectorBiologyVirulenceSecretionSuperresolutionNucleoidComputational biologyLive cell imagingPathogenesisSecretory proteinCell biologyMicrobiologyGeneticsGeneEscherichia coliCellImmunologyBiochemistryComputer scienceImage (mathematics)Artificial intelligenceAdvanced Fluorescence Microscopy TechniquesCell Image Analysis TechniquesBacterial Identification and Susceptibility Testing