Suppression of IRF9 Promotes Osteoclast Differentiation by Decreased Ferroptosis via STAT3 Activation
Chao Lan, Xuan Zhou, Ximei Shen, Youfen Lin, Xiaoyuan Chen, Jiebin Lin, Yongze Zhang, Lifeng Zheng, Sunjie Yan
Topics & Concepts
Gene knockdownOsteoclastOvariectomized ratOsteoimmunologyOsteoporosisCell biologyChemistryIn vitroSTAT3InflammationActivator (genetics)Cancer researchRANKLMedicineImmunologyInternal medicineSignal transductionBiologyGeneBiochemistryEstrogenBone Metabolism and DiseasesCancer-related molecular mechanisms researchRNA modifications and cancer