Seeing the unseen: High-resolution AFM imaging captures antibiotic action in bacterial membranes
Telmo O. Paiva, Albertus Viljoen, Yves F. Dufrêne
Abstract
Advances in atomic force microscopy (AFM) techniques and methodologies for microbiology contribute to our understanding of the microbial cell surface. Recent studies show that AFM imaging of cells and membranes at (near) molecular resolution allows detailed visualization of membranes interacting with drugs.
Topics & Concepts
Atomic force microscopyMembraneNanotechnologyHigh resolutionMicroscopyResolution (logic)Cell membraneBiophysicsMaterials scienceChemistryPhysicsBiologyComputer scienceOpticsRemote sensingBiochemistryArtificial intelligenceGeologyForce Microscopy Techniques and ApplicationsLipid Membrane Structure and BehaviorBacterial biofilms and quorum sensing