Amide cyclodextrin that recognises monophosphate anions in harmony with water molecules
Takashi Nakamura, Hayato Takayanagi, Masaki Nakahata, Takumi Okubayashi, Hitomi Baba, Yoshiki Ishii, Go Watanabe, Daisuke Tanabe, Tatsuya Nabeshima
Abstract
forming hydrogen bonds with the amides, and the hydrophobic effect is a major contributing driving force of the inclusion. The molecular design presented herein to achieve the precise recognition in water and clarification of the detailed mechanisms including the hydration phenomenon greatly contribute to the development of functional molecules that work in aqueous environments.
Topics & Concepts
ChemistryAmideCyclodextrinMoleculeCombinatorial chemistryStereochemistryOrganic chemistryMolecular Sensors and Ion DetectionCrystallography and molecular interactionsAnalytical Chemistry and Chromatography