A simultaneous identification and quantification strategy for determination of sulfhydryl-containing metabolites in normal- and high-fat diet hamsters using stable isotope labeling combined with LC-MS
Lu Chang, Feifei Lin, Kai Cheng, Jiaomeng Li, Xiaochu Sun, Daniel Figeys, Jianlan Jiang, Ye Yang, Jia Liu
Topics & Concepts
ChemistryChromatographyTandem mass spectrometryReagentQuantitative analysis (chemistry)Mass spectrometryMetaboliteGlutathioneIsotopeCysteineMetabolomicsLiquid chromatography–mass spectrometryBiochemistryEnzymeOrganic chemistryQuantum mechanicsPhysicsMetabolomics and Mass Spectrometry StudiesSulfur Compounds in BiologyFolate and B Vitamins Research