A label-free electrochemical aptasensor based on the core–shell Cu-MOF@TpBD hybrid nanoarchitecture for the sensitive detection of PDGF-BB
Ya Li, Zhiling Liu, Wenbo Lu, Man Zhao, He Xiao, Tianjun Hu, Jian‐Chun Ma, Zhanfeng Zheng, Jianfeng Jia, Haishun Wu
Abstract
. The hybridization of MOFs and COFs, together with the immobilization with the specific analyte targeted aptamer, provides a promising and propagable approach to prepare an aptasensor for the simple, sensitive, and selective detection of a specific biomarker in clinical diagnosis.
Topics & Concepts
AptamerDetection limitNanotechnologyChemistryBiomarkerCombinatorial chemistryCovalent bondMetal-organic frameworkPlatelet-derived growth factor receptorMaterials scienceGrowth factorChromatographyBiochemistryMolecular biologyOrganic chemistryBiologyReceptorAdsorptionAdvanced biosensing and bioanalysis techniquesAdvanced Nanomaterials in CatalysisDendrimers and Hyperbranched Polymers