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Increase of PCSK9 expression in diabetes promotes VEGFR2 ubiquitination to inhibit endothelial function and skin wound healing

Jianjun Gao, Fang-Yuan Wu, Yujia Liu, Le Li, Yi‐Jun Lin, Yue-Ting Kang, Yue-Ming Peng, Yifang Liu, Chen Wang, Zhen-Sheng Ma, Yang Cao, Hongyu Cao, Zhi-Wei Mo, Li Yan, Jing‐Song Ou, Zhi‐Jun Ou

2024Science China Life Sciences23 citationsDOI

Topics & Concepts

PCSK9Ubiquitin ligaseDownregulation and upregulationEnosNitric oxideProtein kinase BUbiquitinNitric oxide synthaseChemistryCancer researchMedicineCell biologyEndocrinologyLDL receptorApoptosisBiochemistryBiologyCholesterolLipoproteinGeneLipoproteins and Cardiovascular HealthAtherosclerosis and Cardiovascular DiseasesCoronary Interventions and Diagnostics
Increase of PCSK9 expression in diabetes promotes VEGFR2 ubiquitination to inhibit endothelial function and skin wound healing | Litcius