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Group A Streptococcus induces GSDMA-dependent pyroptosis in keratinocytes

Doris L. LaRock, A. Johnson, Shyra Wilde, Jenna S. Sands, Marcos P. Monteiro, Christopher N. LaRock

2022Nature193 citationsDOIOpen Access PDF

Topics & Concepts

PyroptosisProteasesStreptococcus pyogenesCalpainVirulenceLytic cycleProteaseCysteine proteaseCaspase 1Virulence factorStreptolysinMicrobiologyBiologySerine proteaseEffectorPneumolysinCell biologyImmune systemChemistryInflammasomeVirologyImmunologyVirusBacteriaBiochemistryStaphylococcus aureusGeneticsInflammationEnzymeGeneBacterial proteinInflammasome and immune disordersStreptococcal Infections and TreatmentsToxin Mechanisms and Immunotoxins
Group A Streptococcus induces GSDMA-dependent pyroptosis in keratinocytes | Litcius