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QBT improved cognitive dysfunction in rats with vascular dementia by regulating the Nrf2/xCT/GPX4 and NLRP3/Caspase-1/GSDMD pathways to inhibit ferroptosis and pyroptosis of neurons

Feng Lu, Yijin Wu, Yanrong Yang, Bing‐Jie Yue, Cheng Peng, Chu Chen, Peng Fu, Junrong Du, Fangyi Long

2024International Immunopharmacology13 citationsDOI

Topics & Concepts

PyroptosisDementiaApoptosisCaspaseVascular dementiaMedicineProgrammed cell deathNeuroscienceCell biologyChemistryBiologyBiochemistryPathologyDiseaseFerroptosis and cancer prognosisNeurological Disease Mechanisms and TreatmentsNeuroinflammation and Neurodegeneration Mechanisms
QBT improved cognitive dysfunction in rats with vascular dementia by regulating the Nrf2/xCT/GPX4 and NLRP3/Caspase-1/GSDMD pathways to inhibit ferroptosis and pyroptosis of neurons | Litcius