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Epigenetic therapy potentiates transposable element transcription to create tumor-enriched antigens in glioblastoma cells

H. Josh Jang, Nakul M. Shah, Ju Heon Maeng, Yonghao Liang, Noah L. Basri, Jiaxin Ge, Xuan Qu, Tatenda Mahlokozera, Shin‐Cheng Tzeng, Russell B. Williams, Michael J. Moore, Devi Annamalai, Justin Y. Chen, Hyung Joo Lee, Patrick DeSouza, Daofeng Li, Xiaoyun Xing, Albert H. Kim, Ting Wang

2024Nature Genetics38 citationsDOIOpen Access PDF

Topics & Concepts

Transposable elementBiologyEpigeneticsGlioblastomaDNA Transposable ElementsCancer researchTranscription (linguistics)Epigenetic therapyTranscription factorGeneticsDNA methylationGenomeGeneGene expressionLinguisticsPhilosophyRNA modifications and cancerCRISPR and Genetic EngineeringMicroRNA in disease regulation
Epigenetic therapy potentiates transposable element transcription to create tumor-enriched antigens in glioblastoma cells | Litcius