Construction of coacervates in proteinosome hybrid microcompartments with enhanced cascade enzymatic reactions
Junbo Li, Mei Zhu, Shengliang Wang, Zhengyu Tao, Xiaoman Liu, Xin Huang
Abstract
A spatially segregative coacervate-in-proteinosome hybrid microcompartment is constructed by co-encapsulation of either positively or negatively charged polyelectrolytes within proteinosomes with enhanced cascade enzymatic reactions, providing a step towards the development of artificial eukaryotic cell like microcompartments.
Topics & Concepts
CoacervateCascadeChemistryEnzymePolyelectrolyteBiocatalysisBiophysicsCombinatorial chemistryNanotechnologyBiochemistryMaterials scienceChromatographyCatalysisBiologyOrganic chemistryPolymerReaction mechanismLipid metabolism and biosynthesisPolymer Surface Interaction StudiesLipid Membrane Structure and Behavior